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KMID : 0545120020120060993
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Journal of Microbiology and Biotechnology
2002 Volume.12 No. 6 p.993 ~ p.997
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Glucanhydrolase from Lipomyces starkeyi KSM 22 as Potential Mouthwash Ingredient
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KIM, DOMAN
RYU, SU-JIN/SON, EUN-JU/CHUNG, HYUN-JU/KIM, SEUNG-HEUK/KIM, DO-WON/DAY, DONAL F.
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Abstract
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A glucanhydrolase (a DXAMase exhibiting both dextranolytic and amylolytic activities) from Lipomyces starkeyi KSM 22 hydrolyzed polysaccharides having α-(1→3)-, α-(1→4)-, and α-(1→6)-D-glucosidic likages. The oral hygiene benefits of DXAMase-containing mouthwash were examined in relation to human experimental gingivitis during a 3-week period without brushing. The DXAMase-treated group exhibitied a lower increase in plaque accumulation and gingival index score than the chlorhexidine-treated group. The DXAMase-treated group also showed less tongue accumulation, had taste, and tooth staining, thus indicating a positive role for DXAMase as an antiplaque agent ingredient.
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